Research library / Brain health

BMeta-analysis of RCTs · 38 studies, 1,602 participants

The effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis

B Bonnechère, EB Stephens, AC Boileau, M Ducker, BJ Stubbs. Frontiers in Nutrition. 2026.

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In plain language
Exogenous ketones modestly improved cognitive performance versus placebo (SMD 0.29); no clear difference by formulation; higher dose linked to larger effect.
Limits
Mixed formulations and mostly short tests; disclosures not yet reviewed by us.
Source
doi.org/10.3389/fnut.2026.1802531 · PubMed 42063954

Summary written by Everstack from the published abstract. Verified against Crossref on 2026-10-15. The authors do not endorse Everstack.