Research library / Rapamycin

mTOR inhibition improves immune function in the elderly

J Mannick, G Del Giudice, M Lattanzi, N Valiante, J Praestgaard, B Huang et al.. Science Translational Medicine. 2014.

Published 2026-10-15Sources checked 2026-10-151 sourceEverstack research teamHow we work

In plain language

A short course of the mTOR inhibitor everolimus improved flu vaccine response by about 20%.

Limits

Surrogate endpoint; company funded.

Source

doi.org/10.1126/scitranslmed.3009892 · PubMed 25540326

Summary written by Everstack from the published abstract. Verified against Crossref on 2026-10-15. The authors do not endorse Everstack.