Research library / Fasting and calorie restriction

CRCT secondary analysis · CALERIE participants

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

R Waziry, C Ryan, D Corcoran, K Huffman, M Kobor, M Kothari et al.. Nature Aging. 2023.

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In plain language
Two years of calorie restriction slowed DunedinPACE but not other epigenetic clocks.
Limits
Clock relevance uncertain.
Source
doi.org/10.1038/s43587-022-00357-y · PubMed 37118425 · Free full text

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