DPilot trial · 34 adults with chronic primary insomnia, 28 days

Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study

SM Zick, BD Wright, A Sen, JT Arnedt. BMC Complementary and Alternative Medicine. 2011.

Published 2026-10-15Sources checked 2026-10-151 sourceEverstack research teamHow we work

In plain language: Chamomile extract 270 mg twice a day did not change sleep diary measures versus placebo, including total sleep time and time to fall asleep.
Limits: Small pilot; about 23 mg of apigenin a day by the authors' lab analysis.
Source: doi.org/10.1186/1472-6882-11-78 · PubMed 21939549

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